The hemodynamic power of the heart differentiates normal from diseased right ventricles

Cardiac mechanics is primarily described by the pressure-volume relationship. The ventricular loop displays instantaneous relationship between intraventricular pressure and volume throughout cardiac cycle; however, it does not consider shape of ventricles, their spatiotemporal deformation patterns, how these balance with flowing blood. Our study demonstrates that represents a first level approximation for mechanical power while, at further approximation, importance hemodynamic emerges through patterns fluid dynamics. analysis preliminarily tested in healthy subject’s right ventricle two patients. Moreover, patients’ geometry was then rescaled to present normal volumetric profile verify whether results were affected size or pattern achieved. Results show alterations found abnormal ventricles they directly caused but changes ability gradient generate blood flow. Therefore, physics-based measure takes into account dynamics space-time combination Hemodynamic assessed non-invasively using imaging techniques can be an early indicator dysfunction before occur measurements. These preliminary provide physical ground evaluate its diagnostic prognostic significance future clinical studies.